abstract：:To assess whether the pattern of presentation and the outcome of monoclonal gammopathy of undetermined significance (MGUS) have changed over the last 3 decades, we evaluated 1400 patients, divided into 3 groups: group I (1975-1987), group II (1988-1997), and group III (1998-2007). We observed a significant increase in...

journal_title：Medicine

authors： Varettoni M,Corso A,Cocito F,Mangiacavalli S,Pascutto C,Zappasodi P,Pica G,Lazzarino M

更新日期：2010-07-01 00:00:00

abstract：:Although cardiac troponin I (cTnI) elevation in patients presenting to the hospital with supraventricular tachycardia (SVT) is well recognized, the prevalence, predictors, and prognostic significance of cTnI elevation associated with SVT presentation are not known. We screened records of all patients presenting to 2 h...

journal_title：Medicine

authors： Chow GV,Hirsch GA,Spragg DD,Cai JX,Cheng A,Ziegelstein RC,Marine JE

更新日期：2010-05-01 00:00:00

abstract：:Pyogenic liver abscess is a severe condition and a therapeutic challenge. Treatment failure may be due to an unrecognized ingested foreign body that migrated from the gastrointestinal tract. There has recently been a marked increase in the number of reported cases of this condition, but initial misdiagnosis as cryptog...

journal_title：Medicine

authors： Leggieri N,Marques-Vidal P,Cerwenka H,Denys A,Dorta G,Moutardier V,Raoult D

更新日期：2010-03-01 00:00:00

abstract：:We conducted a single-center retrospective study to compare the characteristics of Takayasu arteritis (TA) among white, North African, and black patients in a French tertiary care center (Hospital Pitié-Salpêtrière, Paris). Eighty-two patients were studied (82.9% female) during a median follow-up of 5.1 years (range, ...

journal_title：Medicine

authors： Arnaud L,Haroche J,Limal N,Toledano D,Gambotti L,Chalumeau NC,Boutin DLTH,Cacoub P,Cluzel P,Koskas F,Kieffer E,Piette JC,Amoura Z

更新日期：2010-01-01 00:00:00

abstract：:We conducted the present study to determine whether subclinical macrovascular atherosclerotic disease was present in patients with ankylosing spondylitis (AS) without clinical history of cardiovascular disease. We also sought to establish whether demographic or clinical features of the disease may influence the develo...

journal_title：Medicine

authors： Gonzalez-Juanatey C,Vazquez-Rodriguez TR,Miranda-Filloy JA,Dierssen T,Vaqueiro I,Blanco R,Martin J,Llorca J,Gonzalez-Gay MA

更新日期：2009-11-01 00:00:00

abstract：:The long-term cardiovascular outcomes of a population-based cohort presenting to the emergency department (ED) with chest pain and classified with a clinical risk stratification algorithm are not well documented. The Olmsted County Chest Pain Study is a community-based study that included all consecutive patients pres...

journal_title：Medicine

authors： Farkouh ME,Aneja A,Reeder GS,Smars PA,Bansilal S,Lennon RJ,Wiste HJ,Razzouk L,Traverse K,Holmes DR Jr,Mathew V

更新日期：2009-09-01 00:00:00

abstract：:Our Renal Care Center (RCC) is a separate building, performing almost 2500 outpatient dialysis runs per month. In May 2007, 2 patients developed, days apart, bacteremia with an apparently identical nonfermentative Gram-negative rod. Because of difficulty identifying the organism, testing in the Biolog system identifie...

journal_title：Medicine

authors： Stevens DA,Hamilton JR,Johnson N,Kim KK,Lee JS

更新日期：2009-07-01 00:00:00

abstract：:Gynecologic vasculitis (GynV) has been reported as part of systemic vasculitis (SGynV) and as single-organ (isolated gynecologic) vasculitis (IGynV). In the current study, we analyzed the clinical and histologic characteristics of patients with GynV and sought to identify features that differentiate the isolated from ...

journal_title：Medicine

authors： Hernández-Rodríguez J,Tan CD,Rodríguez ER,Hoffman GS

更新日期：2009-05-01 00:00:00

abstract：:We conducted the current study to investigate the clinical, laboratory, and histologic features at presentation and the outcome of renal sarcoidosis (RS). Exhaustive retrospective data were collected by the French Sarcoidosis Group. Forty-seven adult patients were assessed (30 male/17 female, M/F ratio: 1.76). Median ...

journal_title：Medicine

authors： Mahévas M,Lescure FX,Boffa JJ,Delastour V,Belenfant X,Chapelon C,Cordonnier C,Makdassi R,Piette JC,Naccache JM,Cadranel J,Duhaut P,Choukroun G,Ducroix JP,Valeyre D

更新日期：2009-03-01 00:00:00

abstract：:Purulent pericarditis, a localized infection within the pericardial space, has become a rare entity in the modern antibiotic era. Although historically a disease of children and young adults, this is no longer the case: the median age at the time of diagnosis has increased by nearly 30 years over the past 6 decades. D...

journal_title：Medicine

authors： Parikh SV,Memon N,Echols M,Shah J,McGuire DK,Keeley EC

更新日期：2009-01-01 00:00:00

abstract：:To investigate the epidemiology of systemic sclerosis (SSc) in southern Europe, we assessed the incidence, prevalence, clinical spectrum, and survival of patients diagnosed with SSc in the Lugo region of northwestern Spain. Between January 1988 and December 2006, SSc was diagnosed in 78 Lugo residents according to the...

journal_title：Medicine

authors： Arias-Nuñez MC,Llorca J,Vazquez-Rodriguez TR,Gomez-Acebo I,Miranda-Filloy JA,Martin J,Gonzalez-Juanatey C,Gonzalez-Gay MA

更新日期：2008-09-01 00:00:00

abstract：:We reviewed the clinical manifestations of mesenteric vasculitis due to giant cell arteritis (GCA) and considered features of the mesenteric anatomy in relationship to disease expression. We compiled and reviewed a case series by systematic identification of patients previously reported in the English-language literat...

journal_title：Medicine

authors： Scola CJ,Li C,Upchurch KS

更新日期：2008-01-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is a febrile disease characterized by acute, spontaneously resolving episodes of fever and pain caused by serosal inflammation and associated with mutations in the FMF gene, MEFV. Prophylaxis is maintained with colchicine. To our knowledge, no study has yet shown an association betwe...

journal_title：Medicine

authors： Tweezer-Zaks N,Doron-Libner A,Weiss P,Ben-Horin S,Barshack I,Lidar M,Livneh A

更新日期：2007-11-01 00:00:00

abstract：:Primary Sjögren syndrome (pSS) is a fairly common autoimmune disease with glandular and extraglandular manifestations. Pulmonary involvement mainly corresponds to small airways and interstitial lung disease. Pulmonary arterial hypertension (PAH) is rare: to our knowledge, only 32 cases have been reported in pSS patien...

journal_title：Medicine

authors： Launay D,Hachulla E,Hatron PY,Jais X,Simonneau G,Humbert M

更新日期：2007-09-01 00:00:00

abstract：:Traditionally, infective endocarditis (IE) has been microbiologically diagnosed by blood cultures or serology. However, conventional microbiologic methods do not always provide an etiologic diagnosis. We conducted the current study to evaluate the usefulness of a universal real-time polymerase chain reaction (PCR) of ...

journal_title：Medicine

authors： Marín M,Muñoz P,Sánchez M,Del Rosal M,Alcalá L,Rodríguez-Créixems M,Bouza E,Group for the Management of Infective Endocarditis of the Gregorio Marañón Hospital (GAME).

更新日期：2007-07-01 00:00:00

abstract：:Severe community-acquired pneumonia (CAP) requiring admission to an intensive care unit (ICU) has been inadequately studied. We compared characteristics and outcomes of patients with CAP who were admitted to the ICU with those of patients managed on the ward. Of the 3675 patients hospitalized with CAP, 374 (10%) were ...

journal_title：Medicine

authors： Marrie TJ,Shariatzadeh MR

更新日期：2007-03-01 00:00:00

abstract：:We conducted a retrospective single-center study to describe the clinical features of sinonasal sarcoidosis (SNS) and to determine whether SNS is associated with a particular clinical phenotype of sarcoidosis. Twenty patients with histologically proven SNS (men/women, 7/13; mean age, 32 +/- 9 yr) were compared with co...

journal_title：Medicine

authors： Aubart FC,Ouayoun M,Brauner M,Attali P,Kambouchner M,Valeyre D,Nunes H

更新日期：2006-11-01 00:00:00

abstract：:We followed prospectively 834 consecutive patients (70% inpatients), evaluated for suspected pulmonary embolism, for a median time of 2.1 years (range, 0-4.8 yr), and compared the survival rates in patients with proven pulmonary embolism (n=320) with those without (n=514). In multivariate analysis, we modeled the prob...

journal_title：Medicine

authors： Miniati M,Monti S,Bottai M,Scoscia E,Bauleo C,Tonelli L,Dainelli A,Giuntini C

更新日期：2006-09-01 00:00:00

abstract：:An infected vascular graft is an uncommon association in hypertrophic osteoarthropathy (HOA) but is important because of potential catastrophic complications. Here we describe 3 new patients with HOA secondary to vascular prosthesis infection and review the other 23 patients described in the English literature with th...

journal_title：Medicine

authors：

更新日期：2006-05-01 00:00:00

abstract：:The idiopathic inflammatory myopathies (IIM) are systemic connective tissue diseases defined by chronic muscle inflammation and weakness associated with autoimmunity. We have performed low to high resolution molecular typing to assess the genetic variability of major histocompatibility complex loci (HLA-A, -B, -Cw, -D...

journal_title：Medicine

authors： O'Hanlon TP,Carrick DM,Targoff IN,Arnett FC,Reveille JD,Carrington M,Gao X,Oddis CV,Morel PA,Malley JD,Malley K,Shamim EA,Rider LG,Chanock SJ,Foster CB,Bunch T,Blackshear PJ,Plotz PH,Love LA,Miller FW

更新日期：2006-03-01 00:00:00

abstract：:We reviewed the clinical, microbiologic, and outcome characteristics of 72 patients with human immunodeficiency virus (HIV)-associated histoplasmosis (4 newly described) reported in Europe over 20 years (1984-2004). Seven cases (9.7%) were acquired in Europe (autochthonous), whereas the majority involved a history of ...

journal_title：Medicine

authors： Antinori S,Magni C,Nebuloni M,Parravicini C,Corbellino M,Sollima S,Galimberti L,Ridolfo AL,Wheat LJ

更新日期：2006-01-01 00:00:00

abstract：:We reviewed 106 patients referred to our institution for treatment of peripheral tuberculous adenitis to establish the epidemiologic, clinical, and pathologic manifestations of this disease. Tuberculous lymphadenitis occurred predominantly in young, foreign-born women a mean of 5 years after arrival in the United Stat...

journal_title：Medicine

authors： Polesky A,Grove W,Bhatia G

更新日期：2005-11-01 00:00:00

abstract：:In the current era of multidrug-resistant organisms, the clinical spectrum of Streptococcus pneumoniae infection remains unclear, especially in immunosuppressed patients with cancer. We sought to define the characteristics of pneumococcal bacteremia in patients who were receiving care at a comprehensive cancer center....

journal_title：Medicine

authors： Kumashi P,Girgawy E,Tarrand JJ,Rolston KV,Raad II,Safdar A

更新日期：2005-09-01 00:00:00

abstract：:Two clinical models have been described to predict the probability of pulmonary embolism: the Canadian (or Wells) model, and the Geneva model. A third model has been developed recently at our institution (the Pisa model). We compared the performance of the 3 models in 215 consecutive patients with suspected pulmonary ...

journal_title：Medicine

authors： Miniati M,Bottai M,Monti S

更新日期：2005-03-01 00:00:00

abstract：:Homeless people are particularly exposed to ectoparasites, but their exposure to arthropod-borne diseases has not been evaluated systematically. A medical team of 27 persons (7 nurses, 6 infectious disease residents or fellows, 2 dermatologists, and 12 infectious disease specialists) visited the 2 shelters in Marseill...

journal_title：Medicine

authors： Brouqui P,Stein A,Dupont HT,Gallian P,Badiaga S,Rolain JM,Mege JL,La Scola B,Berbis P,Raoult D

更新日期：2005-01-01 00:00:00

abstract：:Methemoglobin is a form of hemoglobin that does not bind oxygen. When its concentration is elevated in red blood cells, functional anemia and tissue hypoxia may occur. We performed a retrospective case series to describe the cases of acquired methemoglobinemia (methemoglobin level >2%) detected and the clinical circum...

journal_title：Medicine

authors： Ash-Bernal R,Wise R,Wright SM

更新日期：2004-09-01 00:00:00

abstract：:Primary oculocerebral non-Hodgkin lymphoma (NHL) of the immunocompetent patient is associated with significant morbidity and mortality, but early diagnosis and follow-up may improve prognosis. The eye, anatomically and embryologically part of the central nervous system (CNS), can be the primary site of the lymphomatou...

journal_title：Medicine

authors： Park S,Abad S,Tulliez M,Monnet D,Merlat A,Gyan E,Bouscary D,Dreyfus F,Grimaldi D,Dhote R,Rollot F,Kelaïdi C,Nazal EM,Brézin AP,Blanche P

更新日期：2004-07-01 00:00:00

abstract：:We conducted the current study to search for subclinical atherosclerosis in patients with rheumatoid arthritis (RA) without clinically evident atherosclerosis or its complications who had been treated for a long duration, and to assess whether demographic or clinical factors affect the development of atherosclerotic d...

journal_title：Medicine

authors： Gonzalez-Juanatey C,Llorca J,Testa A,Revuelta J,Garcia-Porrua C,Gonzalez-Gay MA

更新日期：2003-11-01 00:00:00

abstract：:Since the 1990s, changing trends have been documented in species distribution and susceptibility to bloodstream infections caused by Candida species in cancer patients. However, few data are available regarding the association between in vitro antifungal susceptibility and outcome of candidemia in this patient populat...

journal_title：Medicine

authors： Antoniadou A,Torres HA,Lewis RE,Thornby J,Bodey GP,Tarrand JP,Han XY,Rolston KV,Safdar A,Raad II,Kontoyiannis DP

更新日期：2003-09-01 00:00:00

abstract：:Group A streptococcal (GAS) necrotizing fasciitis is a rapidly progressive soft tissue infection. Elderly and chronically ill individuals are at greatest risk, particularly when skin breakdown is present. Reports suggest that nonsteroidal antiinflammatory drugs (NSAIDs) increase the risk of developing GAS necrotizing ...

journal_title：Medicine

authors： Aronoff DM,Bloch KC

更新日期：2003-07-01 00:00:00

abstract：:We describe an easily recognizable and previously not individualized clinical syndrome that can reveal solitary plasmacytoma of bone. We report 4 patients with a slowly extending violaceous skin patch overlying a solitary plasmacytoma of bone, associated with enlarged regional lymph nodes. Biopsies of the cutaneous le...

journal_title：Medicine

authors： Lipsker D,Rondeau M,Massard G,Grosshans E

更新日期：2003-01-01 00:00:00

abstract：:Patients with suspected non-ST-segment elevation acute coronary syndromes (NSTEACS) constitute a heterogeneous population with variable outcomes. Risk stratification in this population of patients is difficult due to the complexity in patient risk profile. We conducted this study to characterize the value of clinical ...

journal_title：Medicine

authors： López de Sá E,López-Sendón J,Anguera I,Bethencourt A,Bosch X,Proyecto de Estudio del Pronostico de la Angina (PEPA) Investigators.

更新日期：2002-11-01 00:00:00

abstract：:(Sca) is a ubiquitous filamentous fungus capable of causing invasive disease. We reviewed our electronic microbiology records and the English-language literature. Between 1976 and December 1999 we identified 23 solid organ transplant recipients with Sca infection, 7 of which occurred between December 1987 and December...

journal_title：Medicine

authors： Castiglioni B,Sutton DA,Rinaldi MG,Fung J,Kusne S

更新日期：2002-09-01 00:00:00

abstract：:We initiated a prospective study with a group of practitioners to assess the etiology, clinical presentation, and outcome of community-acquired pneumonia in patients diagnosed in the outpatient setting. All patients with signs and symptoms suggestive of pneumonia and an infiltrate on chest X-ray underwent an extensive...

journal_title：Medicine

authors： Bochud PY,Moser F,Erard P,Verdon F,Studer JP,Villard G,Cosendai A,Cotting M,Heim F,Tissot J,Strub Y,Pazeller M,Saghafi L,Wenger A,Germann D,Matter L,Bille J,Pfister L,Francioli P

更新日期：2001-03-01 00:00:00

abstract：:Thyroid complications resulting from excess iodide such as thyrotoxicosis, thyroiditis, sialadenitis, or hypothyroidism are much rarer after iodine supplementation with Lipiodol than with KI. They do not militate against its widespread use in endemic goiter populations, especially in pregnant women. However, patients ...

journal_title：Medicine

authors： Wolff J

更新日期：2001-01-01 00:00:00

abstract：:We retrospectively analyzed the long-term outcome of idiopathic pulmonary hemosiderosis (IPH) in 15 children. IPH started at a mean age of 5 years, and the mean duration of follow-up was 17.2 years (range, 10-36 yr). Four patients developed immune disorders, 3 cases of rheumatoid polyarthritis or rheumatoid polyarthri...

journal_title：Medicine

authors： Le Clainche L,Le Bourgeois M,Fauroux B,Forenza N,Dommergues JP,Desbois JC,Bellon G,Derelle J,Dutau G,Marguet C,Pin I,Tillie-Leblond I,Scheinmann P,De Blic J

更新日期：2000-09-01 00:00:00

abstract：:We prospectively identified cases of pneumococcal pneumonia and used stringent criteria to stratify them into bacteremic and nonbacteremic cases. Although patients were distributed among racial groups in proportion to all patients seen at this medical center, the proportion of African-Americans with bacteremic disease...

journal_title：Medicine

authors： Musher DM,Alexandraki I,Graviss EA,Yanbeiy N,Eid A,Inderias LA,Phan HM,Solomon E

更新日期：2000-07-01 00:00:00

abstract：:Hughes (antiphospholipid) syndrome (APS) can mimic multiple sclerosis (MS). We analyzed the clinical, laboratory, and imaging findings of MS-like expression in a cohort of patients with APS in an attempt to identify parameters that might differentiate the 2 entities. We studied 27 patients who were referred to our uni...

journal_title：Medicine

authors： Cuadrado MJ,Khamashta MA,Ballesteros A,Godfrey T,Simon MJ,Hughes GR

更新日期：2000-01-01 00:00:00

abstract：:Although the outcome of renal transplantation in patients with systemic lupus erythematosus (SLE) has been studied, there are few reports about the outcome of patients with systemic sclerosis who have undergone renal transplantation. We retrospectively collected data from the United Network for Organ Sharing (UNOS) Sc...

journal_title：Medicine

authors： Chang YJ,Spiera H

更新日期：1999-11-01 00:00:00

abstract：:Although the association between malignancy and thromboembolic disease is well established, the relative risk of developing initial and recurrent deep vein thrombosis (DVT) or pulmonary embolism (PE) among patients with malignancy versus those without malignancy has not been clearly defined. The Medicare Provider Anal...

journal_title：Medicine

authors： Levitan N,Dowlati A,Remick SC,Tahsildar HI,Sivinski LD,Beyth R,Rimm AA

更新日期：1999-09-01 00:00:00